Emergency Department | Scenario 1

LAI Considerations

• Provide psychoeducation to patient and family on:
  • The high risk of relapse following the discontinuation of maintenance treatment with antipsychotics
    ^3,12,13
  • The advantages of LAIs for the maintenance phase of treatment (ie, less frequent dosing compared to daily orals allows prescribers to easily identify when treatment is discontinued without consulting so psychoeducation can be provided, lower risk of rehospitalization compared to orals)
    ^12,14,15
• In handoff to next level of care (ie, inpatient or outpatient) document discussion on LAIs with patient and family, so this can be followed up on
• If an antipsychotic is restarted in the ER, consider an oral second-generation antipsychotic that has an LAI formulation to allow for an easy transition at a later time point
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