Inpatient Setting | Scenario 3

LAI Considerations

• Discuss LAI of the oral antipsychotic whose tolerability/exposure has been established to improve adherence in the future
  ^13,18
• Accurately measuring adherence remains a significant challenge in schizophrenia. LAIs make it possible to be certain about the adherence status
  ^8,9,19
• LAIs have shown robust efficacy in relapse prevention compared with oral antipsychotics
  ^15,22
• LAI use may take the burden from family/caregiver monitoring of patient adherence and would help clinicians assess whether relapse occurs because of nonadherence or despite adequate medication
  ^19,23